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Impact of Oxygenation Status on (18)F-FDG Uptake in Solid Tumors

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Neveu, Marie-Aline [UCL] Bol, Vanesa [UCL] Bol, Anne [UCL] Grégoire, Vincent [UCL] Gallez, Bernard [UCL]

The influence of changes in tumor oxygenation (monitored by EPR oximetry) on the uptake of (18)F-FDG tracer was evaluated using micro-PET in two different human tumor models. The (18)F-FDG uptake was higher in hypoxic tumors compared to tumors that present a pO2 value larger than 10 mmHg.

Document type Article de périodique (Journal article)
Access type Accès restreint
Publication date 2016
Language Anglais
Journal information "Advances in Experimental Medicine and Biology" - Vol. 876, p. 201-207
Peer reviewed yes
issn 0065-2598
Publication status Publié
Affiliations UCL - SSS/LDRI - Louvain Drug Research Institute
UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie
UCL - (SLuc) Service de radiothérapie oncologique
Links
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Bibliographic reference Neveu, Marie-Aline ; Bol, Vanesa ; Bol, Anne ; Grégoire, Vincent ; Gallez, Bernard. Impact of Oxygenation Status on (18)F-FDG Uptake in Solid Tumors. In: Advances in Experimental Medicine and Biology, Vol. 876, p. 201-207
Permanent URL http://hdl.handle.net/2078.1/172417