Mendelsohn, Abie H
Matar, Nayla
Bachy, Vincent
[UCL]
Lawson, Georges
[UCL]
Remacle, Marc
[UCL]
(eng)
OBJECTIVE: CO2 laser cordectomy for glottic carcinoma offers excellent oncologic control on a per stage basis as compared with primary radiotherapy. We aim to further investigate the fluctuations of postoperative vocal outcomes following extended laser cordectomy for glottic cancer.
DESIGN: Single center retrospective cohort study.
METHODS: Eleven patients with glottic squamous cell carcinoma (SCC) who received CO2 laser cordectomy European Laryngological Society type III-IV with complete datasets at preoperative, immediate postoperative (within 4 months), and delayed (greater than 6 months) time points were included.
RESULTS: All patients (n = 11) received cordectomy as their primary treatment. Tumor stage was divided evenly between T1 and T2. One patient was referred for post-cordectomy thyroplasty. Mean Voice Handicap Index (VHI) scores increased in the immediate postoperative period (43.3-46.2) but did not reach significance (P > 0.05). Delayed postoperative VHI (23.3) demonstrated substantial improvement from both pre- and immediate postoperative levels (P = 0.047). Objective voice rating significantly declined initially (P = 0.03; Grade, P = 0.01; Breathiness) and recovered to similar preoperative levels. Maximum phonation time (MPT) showed substantial decreases at the initial postoperative period (P = 0.007). Although significant improvement was made at the delayed postoperative point (P = 0.009), MPT remained below the preoperative level (P = 0.028). No significant changes were seen in phonatory subglottic pressures.
CONCLUSIONS: Patients undergoing extended CO2 laser cordectomy for glottic cancers can experience initial decline in voice quality; however, vocal function routinely returns to preoperative levels following the initial healing period. A small percentage of extended cordectomy patients may require further vocal interventions.
Bibliographic reference |
Mendelsohn, Abie H ; Matar, Nayla ; Bachy, Vincent ; Lawson, Georges ; Remacle, Marc. Longitudinal Voice Outcomes Following Advanced CO2 Laser Cordectomy for Glottic Cancer.. In: The Journal of Voice, Vol. 29, no. 6, p. 772-775 (2015) |
Permanent URL |
http://hdl.handle.net/2078.1/169945 |