Intestinal transplantation (ITx) is now feasible with actuarial patient and graft survivals at 24 months exceeding 74% and 59%, respectively. The occurrence of opportunistic infections such as cytomegalovirus (CMV), however, has significantly hindered further improvement in long term outcome. In this study, we focus upon our experience with CMV after ITx in children and analyze the influence of CMV infections upon postoperative outcome.