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Adenosine following pulmonary vein isolation to target dormant conduction elimination (ADVICE): methods and rationale

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Macle, Laurent Khairy, Paul Verma, Atul Weerasooriya, Rukshen Willems, Stephan Scavée, Christophe [UCL] ADVICE Study Investigators

Pulmonary vein (PV) isolation (PVI) has emerged as an effective therapy for paroxysmal atrial fibrillation (AF). However, AF recurs in up to 50% of patients, generally because of recovery of PV conduction. Adenosine given during the initial procedure may reveal dormant PV conduction, thereby identifying the need for additional ablation, leading to improved outcomes. The Adenosine Following Pulmonary Vein Isolation to Target Dormant Conduction Elimination (ADVICE) study is a prospective multicentre randomized trial assessing the impact of adenosine-guided PVI in preventing AF recurrences.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2012
Language Anglais
Journal information "Canadian Journal of Cardiology" - Vol. 28, no.2, p. 184-190 (2012)
Peer reviewed yes
Publisher Elsevier Inc. ((United States) New York, NY)
issn 0828-282X
e-issn 1916-7075
Publication status Publié
Affiliations UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire
UCL - (SLuc) Service de cardiologie
MESH Subject Adenosine ; Anti-Arrhythmia Agents ; Atrial Fibrillation ; Humans ; Prospective Studies ; Pulmonary Veins ; Research Design ; Secondary Prevention
Links
Bibliographic reference Macle, Laurent ; Khairy, Paul ; Verma, Atul ; Weerasooriya, Rukshen ; Willems, Stephan ; et. al. Adenosine following pulmonary vein isolation to target dormant conduction elimination (ADVICE): methods and rationale. In: Canadian Journal of Cardiology, Vol. 28, no.2, p. 184-190 (2012)
Permanent URL http://hdl.handle.net/2078.1/158086