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Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis

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Chertow, Glenn M Block, Geoffrey A Correa-Rotter, Ricardo Drüeke, Tilman B Floege, Jürgen Jadoul, Michel [UCL]

In an unadjusted intention-to-treat analysis, cinacalcet did not significantly reduce the risk of death or major cardiovascular events in patients with moderate-to-severe secondary hyperparathyroidism who were undergoing dialysis. (Funded by Amgen; EVOLVE ClinicalTrials.gov number, NCT00345839.).

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2012
Language Anglais
Journal information "The New England journal of medicine" - Vol. 367, no. 26, p. 2482-2494 (2012)
Peer reviewed yes
issn 0028-4793
e-issn 1533-4406
Publication status Publié
Affiliations UCL - SSS/IREC/NEFR - Pôle de Néphrologie
UCL - (SLuc) Service de néphrologie
MESH Subject Adult ; Male ; Middle Aged ; Naphthalenes ; Odds Ratio ; Parathyroid Hormone ; Renal Dialysis ; Aged ; Cardiovascular Diseases ; Female ; Humans ; Hyperparathyroidism, Secondary ; Hypocalcemia ; Intention to Treat Analysis ; Kidney Failure, Chronic
Links
Bibliographic reference Chertow, Glenn M ; Block, Geoffrey A ; Correa-Rotter, Ricardo ; Drüeke, Tilman B ; Floege, Jürgen ; et. al. Effect of cinacalcet on cardiovascular disease in patients undergoing dialysis. In: The New England journal of medicine, Vol. 367, no. 26, p. 2482-2494 (2012)
Permanent URL http://hdl.handle.net/2078.1/135244