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Evaluation of cryopreserved ovarian tissue from prepubertal patients after long-term xenografting and exogenous stimulation.

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Luyckx, Valérie [UCL] Rocha De Azevedo Scalercio, Sarah [UCL] Jadoul , Pascale [UCL] Andrade Amorim, Christiani [UCL] Soares, Michelle [UCL] Donnez, Jacques [UCL] Dolmans, Marie-Madeleine [UCL]

This is the first description of transplantation of human cryopreserved prepubertal ovarian tissue to mice, demonstrating that a very high number of follicles survive after transplantation and a large pool of primordial follicles remains dormant. Growing follicles were observed, proving the responsiveness of prepubertal ovarian tissue to gonadotropins.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2013
Language Anglais
Journal information "Fertility and sterility" - p. 1-9 (2013)
Peer reviewed yes
Publisher Elsevier Sciences Inc (New York, USA)
issn 0015-0282
e-issn 1556-5653
Publication status Publié
Affiliations UCL - SSS/IREC/GYNE - Pôle de Gynécologie
UCL - (SLuc) Service de gynécologie et d'andrologie
Keywords Fertility preservation ; Prepubertal patients ; Cryopreserved ovarian tissue ; Ovarian tissue transplantation ; Xenografting
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Bibliographic reference Luyckx, Valérie ; Rocha De Azevedo Scalercio, Sarah ; Jadoul , Pascale ; Andrade Amorim, Christiani ; Soares, Michelle ; et. al. Evaluation of cryopreserved ovarian tissue from prepubertal patients after long-term xenografting and exogenous stimulation.. In: Fertility and sterility, p. 1-9 (2013)
Permanent URL http://hdl.handle.net/2078.1/134438