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Rat chromosome 2 : Assignment of the genes encoding cyclin B1, interleukin 6 signal transducer, and protein convertase 1 to the Mcs1-containing region and identification of new microsatellite markers

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Szpirer, Claude [ULB] Tissir, Fadel [UCL]

The rat Chromosome (Chr) 2 harbors several genes controlling tumor growth or development, blood pressure, and non-insulin-dependent diabetes mellitus. We report that the region (2q1) containing the mammary susceptibility cancer gene Mcs1 also harbors the genes encoding cyclin B1, interleukin 6 signal transducer (gp130), and proprotein convertase 1. We also generated 13 new anonymous microsatellite markers from Chr 2-sorted DNA. These markers, as well as a microsatellite marker in the cyclin B1 gene, were genetically mapped in combination with known markers. A cyclin B1-related gene was also cytogenetically assigned to rat Chr 11q22-q23

Document type Article de périodique (Journal article) – Article de recherche
Publication date 1999
Language Anglais
Journal information "Mammalian Genome" - Vol. 10, no.1, p. 30-34 (1999)
Peer reviewed yes
Publisher Springer New York LLC ((United States) New York)
issn 0938-8990
e-issn 1432-1777
Publication status Publié
Affiliation UCL - SSS/IONS/CEMO - Pôle Cellulaire et moléculaire
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Bibliographic reference Szpirer, Claude ; Tissir, Fadel ; et. al. Rat chromosome 2 : Assignment of the genes encoding cyclin B1, interleukin 6 signal transducer, and protein convertase 1 to the Mcs1-containing region and identification of new microsatellite markers. In: Mammalian Genome, Vol. 10, no.1, p. 30-34 (1999)
Permanent URL http://hdl.handle.net/2078.1/121055