User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Penicillin-binding proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity of Listeria monocytogenes.

Primary tabs

download
  • Open access
  • PDF
  • 847.93 K
Van de Velde, Sébastien [UCL] Carryn, Stéphane [UCL] Van Bambeke, Françoise [UCL] Hill, Colin Tulkens, Paul M. [UCL] Sleator, Roy D.

While seven penicillin-binding proteins (PBPs) or PBP-like proteins have been identified either by radiolabelled penicillin binding studies or genomic analysis, only PBP3 has been considered of interest for Beta-lactams activity against Listeria monocytogenes. Herein we reveal that both PBP4 and Lmo0441 (a PBP-like protein) play a direct role in cephalosporin activity in L. monocytogenes while PBP4 additionally has a protective affect against both penicillin and carbapenem.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès libre
Publication date 2009
Language Anglais
Journal information "Gut Pathogens" - Vol. 1, p. 23 (2009)
Peer reviewed yes
Publisher BioMed Central Ltd. ((United Kingdom) London)
issn 1757-4749
e-issn 1757-4749
Publication status Publié
Affiliations UCL - MD/FARM - Ecole de pharmacie
UCL - MD/MINT - Département de médecine interne
Links
Bibliographic reference Van de Velde, Sébastien ; Carryn, Stéphane ; Van Bambeke, Françoise ; Hill, Colin ; Tulkens, Paul M. ; et. al. Penicillin-binding proteins (PBP) and Lmo0441 (a PBP-like protein) play a role in Beta-lactam sensitivity of Listeria monocytogenes.. In: Gut Pathogens, Vol. 1, p. 23 (2009)
Permanent URL http://hdl.handle.net/2078.1/106609