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Upper airway obstruction during nasal intermittent positive-pressure hyperventilation in sleep.

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Delguste, Pierre [UCL] Aubert-Tulkens, G Rodenstein, Daniel [UCL]

Episodes of apnoea for up to 1 min were observed in association with hypocapnia caused by passive nasal intermittent positive-pressure mechanical hyperventilation in 3 of 4 patients during sleep. Apnoea seemed to be caused by complete upper airways obstruction; we suggest that this finding was caused by active glottic closure. Avoidance of excessive hypocapnia during positive-pressure ventilation might help to avoid central-nervous-system mediated apnoeic episodes.

Document type Article de périodique (Journal article) – Case Reports, Journal Article, Research Support, Non-U.S. Gov't
Publication date 1991
Journal information "Lancet" - Vol. 338, no. 8778, p. 1295-7 (1991)
Peer reviewed yes
issn 0140-6736
Publication status Publié
Affiliation UCL
MESH Subject Adult ; Electroencephalography ; Electromyography ; Female ; Glottis - physiopathology ; Humans ; Hypocapnia - etiology ; Intermittent Positive-Pressure Ventilation - adverse effects ; Nasal Obstruction - complications - physiopathology ; Sleep Apnea Syndromes - etiology - physiopathology
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Bibliographic reference Delguste, Pierre ; Aubert-Tulkens, G ; Rodenstein, Daniel. Upper airway obstruction during nasal intermittent positive-pressure hyperventilation in sleep.. In: Lancet, Vol. 338, no. 8778, p. 1295-7 (1991)
Permanent URL http://hdl.handle.net/2078.1/10636